Modafinil and Alpha GPC

If you’re wondering whether combining Modafinil with choline is a smart idea. Or if you’re deciding which one to choose. Then you’ve come to the right place. In this article we’ll give you some information about these nootropics. We’ll cover one specific Choline named Alpha GPC, what the benifits are, and whether it should be stacked with Modafinil.

But first. 

What is Modafinil?

Modafinil is a prescription medication used to treat people who feel overly sleepy during the day due to a sleep disorder.

Its effect on the brain is a nootropic, meaning it increases the brain’s cognitive function. It is usually prescribed to sufferers of narcolepsy; however, it is also an effective treatment for obstructive sleep apnea, as well as the general sleepiness from working too late or too long.

Modafinil was discovered to enhance the production of numerous critical neurotransmitters in the brain, including histamine, dopamine, norepinephrine, and serotonin, in a significant way. It has a massive impact on people’s ability to stay awake and alert for long periods of time.

Modafinil’s use has definitely expanded as it is now used to treat memory loss due to dementia, ADHD, jet lag, and weariness induced by lengthy work hours or diseases as it progressively became known for its mood-brightening and memory-enhancing properties, as well as its waking effects.

Today it is used by students, entrepreneurs, and business owners who are looking for a boost in focus and productivity.

Benefits of Modafinil:

• Sharp Memory
• Long-lasting improved memory (12 hours)
• Better cognitive functions
• Heightened productivity
• Increased Focus

Modafinil Side Effects

Potential side effects you may experience are: headaches, nausea, diarrhea, dizziness, nervousness, heartburn, or changes in sexual function. These side effects are usually mild and go away after a week or two. Some people may experience withdrawal symptoms if they suddenly stop taking Provigil.

What is Alpha GPC?

Alpha-glycerophosphocholine (alpha-GPC or -GPC) is a cholinergic compound used to improve cognitive function and boost athletic performance. Additionally, it seems to support cellular membranes, which could slow cognitive aging.

The brain naturally contains alpha glycerylphosphorylcholine, which is crucial for the synthesis of acetylcholine. The blood-brain barrier is easily crossed by Alpha GPC once it has entered the bloodstream in order to provide free forms of choline, which are subsequently transformed into acetylcholine. Acetylcholine levels have been reported to increase 1 to 3 hours after ingesting alpha GPC.

Alpha-GPC is a prescription drug in some European countries. In the US Alpha-GPC can be purchased as a dietary supplement. It is used to treat Alzheimer’s disease, stroke, vascular dementia, dementia brought on by decreased brain blood flow, and memory and cognitive abilities.
Benefits of Alpha GPC

• Improving memory.
• Thinking skills
• Stimulates the production of HGH, which can improve strength
• Improved sleep quality

Alpha GPC Side Effects

Alpha GPC is safe and well tolerated in healthy adults, but there have been reports of adverse effects.

Aside from the rare headaches, exhaustion, nervousness, nausea, diarrhea, and gastrointestinal distress reported by users, this supplement can also make some people feel lightheaded and cause low blood pressure.

Comparing Modafinil and Alpha GPC

Modafinil and Alpha GPC Dosage

Alpha GPC contains around 40% choline by weight, so 1,000 mg of alpha-GPC provides 400 mg of dietary choline. The most frequent label doses for alpha-GPC range from 300 to 600 mg.
The recommended dosage for Modafinil is between 100- 200 mg. The daily dose may be taken as a single dose, usually in the morning.

As with any supplements, it is advisable to begin with the lowest amount that is still helpful and increase it gradually as necessary.

Alpha GPC mechanism of action

In the GI tract and brain, alpha-GPC metabolizes predominantly to choline and glycerophosphate. Acetylcholine (ACh), a neurotransmitter that has been demonstrated to assist a variety of cognitive processes including memory formation and recall, learning capacity, and concentration/focus, is a neurotransmitter that is derived from the amino acid choline. Glycerophosphate, another consequence of alpha-GPC, supports a number of non-nootropic functions, such as healthy cell membrane integrity.

Modafinil mechanism of action

In addition to acting as an atypical, selective, and weak dopamine reuptake inhibitor, Modafinil indirectly triggers the release of histamine and orexin neuropeptides from the tuberomammillary nucleus, which may all help to increase arousal.

Stacking Modafinil with Alpha GPC

There have been people reporting to stack Modafinil with Alpha GPC to reduce headaches from Modafinil. Headaches have been linked to low levels of Choline in red blood cells. This could be the reason the pairing goes so well together. However, in some cases Modafinil headaches are due to people forgetting to drink enough water and becoming dehydrated. Or simply not getting enough sleep.

Furthermore, mixing Modafinil with Alpha GPC appears to be safe when they’re taken at safe doses. If you are experiencing any side effects, stop immediately. Also, consult your doctor before using any of these medicines.

Where to buy Modafinil and Alpha GPC

Alpha GPC is available as a supplement in most countries and can be bought from Amazon. Modafinil is usually a prescription only medicine and can be bought from the pharmacy or from an online source. If you want to buy Modafinil, you can easily do so from our store here.

Read more articles about Modafinil